＜図書＞
Enzyme inhibition in drug discovery and development : the good and the bad / edited by Chuang Lu, Albert P. Li
| データ種別 | 図書 |
|---|---|
| 出版者 | Hoboken, N.J. : Wiley |
| 出版年 | c2010 |
| 大きさ | xiii, 854 p., [8] p. of plates : ill. (some col.) ; 25 cm |
目次／あらすじ
所蔵情報を非表示
| 巻 次 | 配架場所 | 請求記号 | 登録番号 | 状 態 | コメント | ISBN | 刷 年 | 予約 |
|---|---|---|---|---|---|---|---|---|
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3階 | 464.5/L96 | 5011043463 |
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9780470281741 |
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書誌詳細を非表示
| 内容注記 | The drug discovery process / Gerald T. Miwa Medicinal chemistry of the optimization of enzyme inhibitors / Geraldine Harriman, Amy Elder, and Indranath Ghosh Bioanalytical technologies in drug discovery / Jing-Tao Wu Safety biomarkers in drug development : emerging trends and implications / Eric R. Fedyk The role of drug metabolism in drug discovery / Tonika Bohnert and Liang-Shang Gan Applied pharmacokinetics in drug discovery and development / Hua Yang ... [et al.] Enzyme inhibition and inactivation : cytochrome P450 enzymes / R. Scott Obach Cytochrome P450 induction / Edward L. LeCluyse ... [et al.] Inhibition of drug-metabolizing enzymes in gastrointestinal tract and its influence on the drug-drug interaction prediction / Aleksandra Galetin and J. Brian Houston Enzyme inhibition in various in vitro systems / Ping Zhao Cytochrome P450 degradation and its clinical relevance / Mingxiang Liao ... [et al.] Complexities of working with UDP-glucuronosyltransferases (UGTs) : focus on enzyme inhibition / Michael B. Fisher Evaluation of inhibitors of drug metabolism in human hepatocytes / Albert P. Li and Chuang Lu Grapefruit juice and its constituents as new esterase inhibitors / Suresh K. Balani Transporter-xenobiotic interactions : an important aspect of drug development studies / Gang Luo, Richard Ridgewell, and Thomas Guenthner Polymorphisms of drug transporters and their clinical implications / Cindy Q. Xia and Johnny J. Yang Clinical drug interactions due to metabolic inhibition : prediction, assessment, and interpretation / Lisa L. von Moltke and David J. Greenblatt Predicting interindividual variability of metabolic drug-drug interactions : identifying the causes and accounting for them using a systems approach / Amin Rostami-Hodjegan NF-kB : mechanism, tumor biology, and inhibitors / Lenny Dang G-protein-coupled receptors as drug targets / Wenyan Miao and Lijun Wu Pharmacological modulation of ion channels for the treatment of chronic pain / Yi Liu and Ning Qin Targeting the mTOR pathway for tumor therapeutics / Wei Chen HIV-1 protease inhibitors as antiretroviral agents / Sergei V. Gulnik, Elena Afonina, and Michael Eissenstat |
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| 一般注記 | Includes bibliographical references and index |
| 著者標目 | Lu, Chuang Li, A. P. |
| 件 名 | LCSH:Enzyme inhibitors LCSH:Drug development LCSH:Drugs -- Metabolism 全ての件名で検索 MESH:Enzyme Inhibitors -- pharmacology 全ての件名で検索 MESH:Drug Discovery -- methods 全ての件名で検索 MESH:Enzyme Inhibitors -- chemical synthesis 全ての件名で検索 |
| 分 類 | LCC:QP601.5 DC22:615/.19 |
| 書誌ID | 2000100986 |
| ISBN | 9780470281741 (cloth) |
| NCID | GB46962392 |
目次／あらすじ