＜図書＞
Anticancer agents from natural products / edited by Gordon M. Cragg, David G.I. Kingston, and David J. Newman
| データ種別 | 図書 |
|---|---|
| 版 | 2nd ed |
| 出版者 | Boca Raton : CRC Press |
| 出版年 | c2012 |
| 大きさ | xv, 751 p. : ill. (some col.) ; 26cm |
目次／あらすじ
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| 巻 次 | 配架場所 | 請求記号 | 登録番号 | 状 態 | コメント | ISBN | 刷 年 | 予約 |
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3階 | 491.65/C91 | 5012050294 |
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9781439813829 |
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書誌詳細を非表示
| 一般注記 | Summary: "This book covers clinically used anticancer agents that are either natural products or are clearly derived from natural product leads. The second edition includes drugs that are currently in development. In addition, the text emphasizes the applications of synthetic and medicinal chemistry to the preparation of analogs with enhanced activities. Contributors also address the potential of novel drug discovery through the use of genome mining as well as the status of advanced development candidates. For each compound of class of compounds, the text provides information on the history, structure, mechanism of action, development, synthesis, medicinal chemistry, and clinical applications"-- Provided by publisher Summary: "The search for new lead compounds is a crucial element of modern pharmaceutical research. Natural products provided the only source of pharmaceuticals for thousands of years, and natural products have made enormous contributions to human health through compounds such as quinine, morphine, aspirin (a natural product analog), digitoxin, and many others. The potential of natural products as anticancer agents was recognized in the 1950's by the U. S. National Cancer Institute (NCI) under the leadership of the late Dr. Jonathan Hartwell, and the NCI has since made major contributions to the discovery of new naturally occurring anticancer agents through its contract and grant support, including an important program of plant and marine collections. Many, although not all, of the compound classes described in the following pages owe their origin in whole or in part to NCI support. In spite of the success of the natural products approach to anticancer drug discovery, as exemplified by the following chapters, |
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| 著者標目 | Cragg, Gordon M. L. Kingston, David G. I. Newman, David J. |
| 件 名 | LCSH:Antineoplastic agents LCSH:Pharmacognosy LCSH:Natural products FREE:SCIENCE / Chemistry / General. bisacsh |
| 分 類 | LCC:RS431.A64 DC22:616.99/4061 |
| 書誌ID | 2000113357 |
| ISBN | 9781439813829 (hardback) |
| NCID | GB60351730 |
目次／あらすじ